CD3 anticorps (PE)
Aperçu rapide pour CD3 anticorps (PE) (ABIN490264)
Antigène
Voir toutes CD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
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Purification
- Protein A purified
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Immunogène
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Purified human CD3 proteins isolated from thymus.
Type of Immunogen: Purified protein -
Isotype
- IgG1
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Indications d'application
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Approved: Flo
Usage: The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 microgram/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 15 mM sodium azide, 0.2 % BSA, PBS
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze. Product is photosensitive and should be protected from light.
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Stock
- 4 °C
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Stockage commentaire
- Store at 4°C. Do not freeze. Protect from light.
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- CD3
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Autre désignation
- CD3
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Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
Antigène
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